baclofenA recent study, published in the Journal of European Neuropsychopharmacology demonstrates that the drug Baclofen is actually not as effective at treating alcohol dependency as was previously thought.

It had been marketed as the new wonder treatment, but a fully randomised, placebo controlled trial conducted in the Netherlands showed no significant difference between patients who took a high dose (150 mg/day), a low dose (30 mg/day), or those who took a placebo (both groups were also receiving counselling). Relapse rates were effectively the same across all three groups.

The study authors conclude quite rightly that the widespread ‘off-label’ prescription of Baclofen for alcohol dependence should be reconsidered.